Tag: dna

Cannabis, Genetics, and Schizophrenia: Unraveling the Correlation

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A study on genetics and cannabis found a connexion between marijuana use and genetic states. The study claimed to be looking for epigenetic effects and although there were some correlations, the directions of causality haven’t been determined.

Recent research has delved into the complex interplay between genetics and cannabis use, revealing intriguing correlations but leaving some critical questions unanswered. A recent study aimed to uncover the epigenetic effects of marijuana use, suggesting a link between genetic states and cannabis consumption. Whilst the findings offer some fascinating insights, they also highlight the ambiguity surrounding causality.

The Genetic Link

The study in question sought to explore whether cannabis use might influence genetic expression or, conversely, whether genetic predispositions could affect an individual’s likelihood of using marijuana. The results indicated some noteworthy correlations between cannabis use and certain genetic states, yet they fell short of clarifying the direction of causality. In other words, the research raises important questions but doesn’t definitively answer whether cannabis use leads to changes in genetic expression or if genetic predispositions increase the likelihood of cannabis use.

Cannabis and Schizophrenia: A Complicated Relationship

One of the most contentious aspects of the study is its implications for understanding the relationship between cannabis use and schizophrenia. The association between the two has been a subject of ongoing debate, with some evidence suggesting a connection. However, the study’s findings underscore the complexity of this relationship. It remains unclear whether cannabis use contributes to the development of schizophrenia or if individuals with a predisposition to schizophrenia are more likely to use cannabis.

The ambiguity stems from the fact that whilst correlations exist, they do not establish a clear cause-and-effect relationship. Schizophrenia is a multifactorial disorder, influenced by a combination of genetic, environmental, and neurobiological factors. Cannabis use might interact with these factors, but pinning down the exact nature of this interaction remains elusive.

What’s Next?

This study serves as a reminder of the challenges inherent in unraveling the connections between genetics and behaviour. It highlights the need for further research to elucidate the causal pathways and better understand how genetic predispositions and environmental factors like cannabis use interact. Until then, while correlations provide valuable insights, they are insufficient to draw definitive conclusions about causality.

As research progresses, it’s crucial to approach these findings with a nuanced perspective, recognising that the relationship between cannabis, genetics, and mental health is complex and multifaceted. Continued exploration in this area will hopefully shed more light on these intricate connections and help guide future investigations.

The Fragility of Our Systems: A Reflection on Noble vs. Dawkins

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Denis Noble’s critique of Richard Dawkins’ approach to genetics isn’t just a scientific debate; it’s a microcosm of a much larger issue: our inadequate grasp of systems thinking. This inadequacy resonates through every layer of our social, political, and economic frameworks, revealing why these systems often fail us—they are simply too fragile.

VIDEO: Denis Noble explains his revolutionary theory of genetics | Genes are not the blueprint for life

Why do we struggle with systems thinking? The concept itself demands an understanding of boundaries, dimensions, and interactions that are often far beyond our regular scope. More often than not, we define system boundaries too narrowly. We overlook crucial dimensions and, crucially, miss the interactions. This isn’t just an academic observation; it’s a practical one. In my experience, even when we do acknowledge broader boundaries, management frequently undermines their importance, limiting the scope of what’s considered relevant.

Humans Are Abysmal Systems Thinkers

Since the 1980s, my interest in genetics has been piqued by Dawkins’ seminal works like The Selfish Gene and The Blind Watchmaker. Dawkins has long championed a gene-centric view of evolution, one that has shaped our understanding of biology for decades. However, Denis Noble challenges this perspective, advocating for a systems-level view that considers not just the genes but the interactions between a myriad of biological processes. This isn’t just genetics; it’s a profound illustration of systems thinking—or our lack thereof.

I’m not suggesting we discard Dawkins’ contributions to science, but Noble’s arguments are compelling and warrant serious consideration. They underscore a broader philosophical dilemma: our rhetorical constructs often overshadow deeper truths. In discussing the nuances between Dawkins’ and Noble’s theories, I argue that rhetoric, for better or worse, becomes our only accessible truth. While there may be more fundamental truths out there, they are often beyond our grasp, obscured not just by our cognitive limitations but also by the very language we use to discuss them.

So, which is true? The answer might be less about choosing sides and more about acknowledging our limitations in understanding and managing complex systems. Perhaps it’s time to consider that in the quest for truth, acknowledging our blind spots is just as important as the truths we defend.

Apologies in advance for linking a teaser video that leads to a paywall, but the relevant content is self-contained.