Tag: causation

Cannabis, Genetics, and Schizophrenia: Unraveling the Correlation

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A study on genetics and cannabis found a connexion between marijuana use and genetic states. The study claimed to be looking for epigenetic effects and although there were some correlations, the directions of causality haven’t been determined.

Recent research has delved into the complex interplay between genetics and cannabis use, revealing intriguing correlations but leaving some critical questions unanswered. A recent study aimed to uncover the epigenetic effects of marijuana use, suggesting a link between genetic states and cannabis consumption. Whilst the findings offer some fascinating insights, they also highlight the ambiguity surrounding causality.

The Genetic Link

The study in question sought to explore whether cannabis use might influence genetic expression or, conversely, whether genetic predispositions could affect an individual’s likelihood of using marijuana. The results indicated some noteworthy correlations between cannabis use and certain genetic states, yet they fell short of clarifying the direction of causality. In other words, the research raises important questions but doesn’t definitively answer whether cannabis use leads to changes in genetic expression or if genetic predispositions increase the likelihood of cannabis use.

Cannabis and Schizophrenia: A Complicated Relationship

One of the most contentious aspects of the study is its implications for understanding the relationship between cannabis use and schizophrenia. The association between the two has been a subject of ongoing debate, with some evidence suggesting a connection. However, the study’s findings underscore the complexity of this relationship. It remains unclear whether cannabis use contributes to the development of schizophrenia or if individuals with a predisposition to schizophrenia are more likely to use cannabis.

The ambiguity stems from the fact that whilst correlations exist, they do not establish a clear cause-and-effect relationship. Schizophrenia is a multifactorial disorder, influenced by a combination of genetic, environmental, and neurobiological factors. Cannabis use might interact with these factors, but pinning down the exact nature of this interaction remains elusive.

What’s Next?

This study serves as a reminder of the challenges inherent in unraveling the connections between genetics and behaviour. It highlights the need for further research to elucidate the causal pathways and better understand how genetic predispositions and environmental factors like cannabis use interact. Until then, while correlations provide valuable insights, they are insufficient to draw definitive conclusions about causality.

As research progresses, it’s crucial to approach these findings with a nuanced perspective, recognising that the relationship between cannabis, genetics, and mental health is complex and multifaceted. Continued exploration in this area will hopefully shed more light on these intricate connections and help guide future investigations.

Moral Responsibility

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Can we be held morally responsible for our actions? Yes, says Daniel Dennett. No, says Gregg Caruso. Reader, you decide

Aeon Article, 4 October 2018

Caruso: [Dan,] you have famously argued that freedom evolves and that humans, alone among the animals, have evolved minds that give us free will and moral responsibility. I, on the other hand, have argued that what we do and the way we are is ultimately the result of factors beyond our control, and that because of this we are never morally responsible for our actions, in a particular but pervasive sense – the sense that would make us truly deserving of blame and praise, punishment and reward. While these two views appear to be at odds with each other, one of the things I would like to explore in this conversation is how far apart we actually are. I suspect that we may have more in common than some think – but I could be wrong. To begin, can you explain what you mean by ‘free will’ and why you think humans alone have it?

Gregg Caruso

Dennett: A key word in understanding our differences is ‘control’. [Gregg,] you say ‘the way we are is ultimately the result of factors beyond our control’ and that is true of only those unfortunates who have not been able to become autonomous agents during their childhood upbringing. There really are people, with mental disabilities, who are not able to control themselves, but normal people can manage under all but the most extreme circumstances, and this difference is both morally important and obvious, once you divorce the idea of control from the idea of causation. Your past does not control you; for it to control you, it would have to be able to monitor feedback about your behaviour and adjust its interventions – which is nonsense.

In fact, if your past is roughly normal, it contains the causal chains that turned you into an autonomous, self-controlling agent. Lucky you. You weren’t responsible for becoming an autonomous agent, but since you are one, it is entirely appropriate for the rest of us to hold you responsible for your deeds under all but the most dire circumstances. 

Daniel Dennett

if your past is roughly normal, it contains the causal chains that turned you into an autonomous, self-controlling agent

Dan Dennett

So commences this debate. The argument unfolds largely on semantic grounds. Even here, one can see the debate over the distinction between control and causation. I understand what Dennett is attempting to parse here, but I object on the grounds of causa sui.

I recommend reading the Aeon article as there is much more than this distinction, but it does remain a semantic issue. I started a post on backwards- and forward-looking perspectives, that better articulate Caruso’s perspective, but I am also working on other things. This was quicker to post and I wanted to keep a bookmark anyway, so it’s a win-win.